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For example, humans have a diploid genome that usually contains 22 pairs of autosomes and one allosome pair (46 chromosomes total).

The autosome pairs are labeled with numbers (1–22 in humans) roughly in order of their sizes in base pairs, while allosomes are labelled with their letters.

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Clinical geneticists can compare the karyogram of an individual to a reference karyogram to discover the cytogenetic basis of certain phenotypes.

For example, the karyogram of someone with Patau Syndrome would show that they possess three copies of chromosome 13.

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